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研究業績-2015年

2015年

論文、総説等

R. Yoshimura, M. Takai, H. Namaki, K. Minami, W. Imamura, H. Kato, Y. Kamei, R. Kanamoto. Down regulation of asparagine synthetase and 3-phosphoglycerate dehydrogenase, and the up-regulation of serine dehydratase in rat liver from intake of excess amount of leucine are not related to leucine-caused amino acid imbalance. J Nutr Sci Vitaminol. 61:441-8, 2015. [PubMed]

N. Senoo, N. Miyoshi, N. Goto-Inoue, K. Minami, R. Yoshimura, A. Morita, N. Sawada, J. Matsuda, Y. Ogawa, M. Setou, Y. Kamei*, S. Miura*. PGC-1α-mediated changes in phospholipid profiles of exercise-trained skeletal muscle. J Lipid Res. 56:2286-96, 2015. (*Corresponding Author) [PubMed]

Y. Hatazawa, N. Senoo, M. Tadaishi, Y. Ogawa, O. Ezaki, Y. Kamei*, S. Miura*. Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α. PLoS One. 10:e0129084, 2015. doi: 10.1371/journal.pone.0129084. 2015. (*Corresponding Author) [PubMed]
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129084

Y. Kamei, Y. Hatazawa, R. Yoshimura, S. Miura. PGC-1α, A Stimuli-Inducible Nuclear Receptor Coactivator: Structural Features and Role in Skeletal Muscle Metabolism Gene Regulation. RNA and Transcription 1:6-9, 2015. http://www.sciencepublishinggroup.com/journal/archive.aspx?journalid=362&issueid=-1

T. Ehara, Y. Kamei, X. Yuan, M. Takahashi, S. Kanai, K. Tsujimoto, T. Tamiya, Y. Nakagawa, H. Shimano, T. Takai-Igarashi, I. Hatada, T. Suganami, K. Hashimoto, Y. Ogawa. Ligand-activated PPARα-dependent DNA demethylation regulates the fatty acid β-oxidation genes in the postnatal liver. Diabetes 64:775-84, 2015. [PubMed]

M. Takagi, H. Uno, R. Nishi, M. Sugimoto, S. Hasegwa, J. Piao, N. Ihara, S. Kanai, S. Kakei, Y. Tamura, T. Suganami, Y. Kamei, T. Shimizu, A. Yasuda, Y. Ogawa, S. Mizutani. ATM regulates adipocyte differentiation and contributes to glucose homeostasis Cell Reports, S2211-1247(15)00052-2, 2015. [PubMed]

亀井康富,小川佳宏 「骨格筋からみた糖尿病の病態と治療」月刊糖尿病 医学出版 vol.7 No1 p.80-85, 2015
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山下敦史、亀井康富「骨格筋と脂肪組織にかかわる最近の話題」、『化学と生物』、日本農芸化学会 会誌、第53巻1号、5-6、2015
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吉村亮二、亀井康富 「骨格筋とオートファジー」 内分泌・糖尿病・代謝内科 vol 40, 445-452, 2015

学会発表等

12TH Asian Congress of Nutrition 14-18 May 2015, Yokohama, Japan
(Symposium)
Molecular mechanism of gene expression in skeletal muscle function and amino acid metabolism
Yasutomi Kamei, Shinji Miura, Yoshihiro Ogawa 

(Poster)
Effect of PGC-1alpha on exercise capacity in mice
Kimiko Minami, Ryoji Yoshimura, Yasutomi Kamei

(Poster)
The role of transcriptional factor FOXO1 in satellite cell action
Atsushi Yamashita, Yukino Hatazawa, Shinji Miura, Yusuke Ono, Yasutomi Kamei 

(Oral, Young Investigator Award)
PGC1alpha regulates branched-chain amino acid metabolism in the skeletal muscle
Yukino Hatazawa, Miki Tadaishi, Yoshihiro Ogawa, Osamu Ezaki, Yasuyuki Kitaura, Yoshiharu Shimomura, Yasutomi Kamei, Shinji Miura 

(Oral)
Effect of PGC-1a on branched chain amino acid intake in mice
Ryoji Yoshimura, Kimiko Minami, Yasutomi Kamei